BDBM50125747 CHEMBL276012::N-[2-(4-Butyryl-4-phenyl-piperidin-1-yl)-1-(4-methoxy-benzyl)-2-oxo-ethyl]-2-hydroxy-3-(1H-imidazol-4-yl)-propionamide

SMILES CCCC(=O)C1(CCN(CC1)C(=O)[C@@H](Cc1ccc(OC)cc1)NC(=O)[C@H](O)Cc1cnc[nH]1)c1ccccc1

InChI Key InChIKey=PKLZEDVDEGTAFP-KAYWLYCHSA-N

Data  1 IC50  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50125747   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125747(CHEMBL276012 | N-[2-(4-Butyryl-4-phenyl-piperidin-...)
Affinity DataEC50:  3.80nMAssay Description:In vitro effective concentration towards human Melanocortin 1 receptor (MC1R) in SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125747(CHEMBL276012 | N-[2-(4-Butyryl-4-phenyl-piperidin-...)
Affinity DataEC50:  3.90E+3nMAssay Description:In vitro effective concentration towards human Melanocortin-3 receptor (MC3R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125747(CHEMBL276012 | N-[2-(4-Butyryl-4-phenyl-piperidin-...)
Affinity DataEC50:  77nMAssay Description:In vitro effective concentration towards human Melanocortin 4 receptor (MC4R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125747(CHEMBL276012 | N-[2-(4-Butyryl-4-phenyl-piperidin-...)
Affinity DataEC50:  2.70E+3nMAssay Description:In vitro effective concentration towards human Melanocortin 5 receptor (MC5R) was determined by a SPA-based cAMP assay in melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50125747(CHEMBL276012 | N-[2-(4-Butyryl-4-phenyl-piperidin-...)
Affinity DataIC50:  5.5nMAssay Description:In vitro inhibitory concentration of the compound against human Melanocortin 1 receptor (MC1R)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed