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BDBM50125825 CHEMBL3623892

InChI string: InChI=1S/C24H22N6O/c1-17-13-19(9-10-26-17)18-3-6-21(7-4-18)30(2)16-24(31)29-23-8-5-20(14-28-23)22-15-25-11-12-27-22/h3-15H,16H2,1-2H3,(H,28,29,31)

SMILES: CN(CC(=O)Nc1ccc(cn1)-c1cnccn1)c1ccc(cc1)-c1ccnc(C)c1

InChI Key: InChIKey=ZGRBWKLEMFYLEU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125825   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50125825
PNG
(CHEMBL3623892)
Show SMILES CN(CC(=O)Nc1ccc(cn1)-c1cnccn1)c1ccc(cc1)-c1ccnc(C)c1
Show InChI InChI=1S/C24H22N6O/c1-17-13-19(9-10-26-17)18-3-6-21(7-4-18)30(2)16-24(31)29-23-8-5-20(14-28-23)22-15-25-11-12-27-22/h3-15H,16H2,1-2H3,(H,28,29,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 0.670n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)

More data for this
Ligand-Target Pair