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BDBM50125827 CHEMBL3623890

InChI string: InChI=1S/C23H24N6O3/c1-17(30)28-10-12-29(13-11-28)19-3-5-20(6-4-19)32-16-23(31)27-22-7-2-18(14-26-22)21-15-24-8-9-25-21/h2-9,14-15H,10-13,16H2,1H3,(H,26,27,31)

SMILES: CC(=O)N1CCN(CC1)c1ccc(OCC(=O)Nc2ccc(cn2)-c2cnccn2)cc1

InChI Key: InChIKey=CDFKDSAHIOQTEA-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125827   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50125827
PNG
(CHEMBL3623890)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(OCC(=O)Nc2ccc(cn2)-c2cnccn2)cc1
Show InChI InChI=1S/C23H24N6O3/c1-17(30)28-10-12-29(13-11-28)19-3-5-20(6-4-19)32-16-23(31)27-22-7-2-18(14-26-22)21-15-24-8-9-25-21/h2-9,14-15H,10-13,16H2,1H3,(H,26,27,31)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a 483n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)

More data for this
Ligand-Target Pair