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BDBM50125829 CHEMBL3623889

InChI string: InChI=1S/C22H21N5O3/c1-15(28)27-9-6-16-2-4-19(10-18(16)13-27)30-14-22(29)26-21-5-3-17(11-25-21)20-12-23-7-8-24-20/h2-5,7-8,10-12H,6,9,13-14H2,1H3,(H,25,26,29)

SMILES: CC(=O)N1CCc2ccc(OCC(=O)Nc3ccc(cn3)-c3cnccn3)cc2C1

InChI Key: InChIKey=NYBVWXCUMDDIPH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125829   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50125829
PNG
(CHEMBL3623889)
Show SMILES CC(=O)N1CCc2ccc(OCC(=O)Nc3ccc(cn3)-c3cnccn3)cc2C1
Show InChI InChI=1S/C22H21N5O3/c1-15(28)27-9-6-16-2-4-19(10-18(16)13-27)30-14-22(29)26-21-5-3-17(11-25-21)20-12-23-7-8-24-20/h2-5,7-8,10-12H,6,9,13-14H2,1H3,(H,25,26,29)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

AffyNet 
PubMed
n/an/a 24n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)

More data for this
Ligand-Target Pair