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BDBM50125898 CHEMBL3623880

InChI string: InChI=1S/C21H16N4O2/c26-21(14-27-18-7-5-15-3-1-2-4-16(15)11-18)25-20-8-6-17(12-24-20)19-13-22-9-10-23-19/h1-13H,14H2,(H,24,25,26)

SMILES: O=C(COc1ccc2ccccc2c1)Nc1ccc(cn1)-c1cnccn1

InChI Key: InChIKey=FNZKUKLUIGSDDI-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125898   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein-serine O-palmitoleoyltransferase porcupine


(Homo sapiens)
BDBM50125898
PNG
(CHEMBL3623880)
Show SMILES O=C(COc1ccc2ccccc2c1)Nc1ccc(cn1)-c1cnccn1
Show InChI InChI=1S/C21H16N4O2/c26-21(14-27-18-7-5-15-3-1-2-4-16(15)11-18)25-20-8-6-17(12-24-20)19-13-22-9-10-23-19/h1-13H,14H2,(H,24,25,26)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
AffyNet 
PubMed
n/an/a>1.00E+3n/an/an/an/an/an/a



Soochow University

Curated by ChEMBL


Assay Description
Inhibition of porcupine (unknown origin) expressed in mouse L Wnt3A cells co-cultured with TM3 cells harboring luciferase reporter gene assessed as r...


Bioorg Med Chem 23: 6855-68 (2015)

More data for this
Ligand-Target Pair