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BDBM50125934 3-(1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid 2-(3-methyl-3H-diazirin-3-yl)-ethyl ester::CHEMBL23812

SMILES: CC(c1ccccc1)n1cncc1C(=O)OCCC1(C)N=N1

InChI Key: InChIKey=DUOHNSBKYJHAMQ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50125934   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nicotinic acetylcholine receptor alpha1/beta1/gamma/delta


(MOUSE-Mus musculus)
BDBM50125934
PNG
(3-(1-Phenyl-ethyl)-3H-imidazole-4-carboxylic acid ...)
Show SMILES CC(c1ccccc1)n1cncc1C(=O)OCCC1(C)N=N1
Show InChI InChI=1/C16H18N4O2/c1-12(13-6-4-3-5-7-13)20-11-17-10-14(20)15(21)22-9-8-16(2)18-19-16/h3-7,10-12H,8-9H2,1-2H3
PDB
MMDB

KEGG

GoogleScholar
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.50E+4n/an/an/an/an/an/a



Massachusetts General Hospital

Curated by ChEMBL


Assay Description
Inhibition of recombinant embryonic mouse muscle Nicotinic Acetylcholine Receptor (3 oocytes)


J Med Chem 46: 1257-65 (2003)


Article DOI: 10.1021/jm020465v
BindingDB Entry DOI: 10.7270/Q24J0FVZ
More data for this
Ligand-Target Pair