BDBM50126164 CHEMBL3416132

SMILES Clc1ccc2CCNC(=O)c2c1

InChI Key InChIKey=NMZRTRAYSHQMPR-UHFFFAOYSA-N

Data  2 KI  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50126164   

TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataKi:  8.90E+6nMAssay Description:Inhibition of recombinant human factor-7a/TF using S2288 as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetCoagulation factor VII/Tissue factor(Homo sapiens (Human))
Bristol-Myers Squibb R & D

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataKi:  8.90E+6nMAssay Description:Inhibition of human soluble tissue factor/factor VIIa expressed in Origami B (DE3) using D-Ile-Pro-Arg-pNA as substrate after 30 mins by spectrophoto...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of PARP-10 (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of PARP-10 L926G mutant (unknown origin) mediated ADP-ribosylation of SRPK2 by fluorescence analysis using 3 uM SRPK2 as a substrateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Oregon Health & Science University

Curated by ChEMBL
LigandPNGBDBM50126164(CHEMBL3416132)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of PARP1 (unknown origin) by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed