BDBM50126349 2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperazin-1-yl)methyl)-6-methoxy-3,4-dihydronaphthalen-1(2H)-one::2-(4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-piperazin-1-ylmethyl)-6-methoxy-3,4-dihydro-2H-naphthalen-1-one::CHEMBL27748

SMILES COc1ccc2C(=O)C(CN3CCN(CCOC(c4ccc(F)cc4)c4ccc(F)cc4)CC3)CCc2c1

InChI Key InChIKey=YHMABVAVFRAMNQ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50126349   

TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Heights

Curated by ChEMBL
LigandPNGBDBM50126349(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...)
Affinity DataKi:  2.96nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
University Heights

Curated by ChEMBL
LigandPNGBDBM50126349(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...)
Affinity DataKi:  3nMAssay Description:Binding affinity towards rat serotonin transporter (SERT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126349(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...)
Affinity DataKi:  22nMAssay Description:Binding affinity of the compound towards dopamine transporter (DAT)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126349(2-((4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperaz...)
Affinity DataKi:  22nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed