BDBM50126393 CHEMBL417853::N-Benzhydryl-N-{[carbamoylmethyl-((R)-1-phenyl-ethyl)-carbamoyl]-methyl}-2-(3-guanidino-propylamino)-acetamide

SMILES C[C@@H](N(CC(N)=O)C(=O)CN(C(c1ccccc1)c1ccccc1)C(=O)CNCCCNC(N)=N)c1ccccc1

InChI Key InChIKey=JKHFKJGWQYBAFO-HSZRJFAPSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50126393   

TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  2.50E+4nMAssay Description:Inhibitory activity of the compound against hMC1R (human melanocortin receptor) using [125I]- ASIP Y radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity of the compound against hMC3R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  1.90E+3nMAssay Description:Binding affinity of the compound against human melanocortin 4 receptor (hMC4R) using [125I]- agouti related protein (AGRP) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  1.90E+3nMAssay Description:Binding affinity of the compound against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibitory activity of the compound against hMC1R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  3.10E+3nMAssay Description:Binding affinity of the compound against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory activity of the compound against hMC4R (human melanocortin receptor) using [125I]-[Nle4] alpha-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  3.10E+3nMAssay Description:Binding affinity of the compound against human melanocortin 4 receptor (hMC4R) using [125I]- ([Nle4]alpha-MSH) as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50126393(CHEMBL417853 | N-Benzhydryl-N-{[carbamoylmethyl-((...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibitory activity of the compound against hMC4R (human melanocortin receptor) using I-AGRP as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed