BDBM50126820 1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy)ethyl)piperidine::4-{2-[Bis-(4-fluoro-phenyl)-methoxy]-ethyl}-1-(4-nitro-benzyl)-piperidine::CHEMBL290799

SMILES [O-][N+](=O)c1ccc(CN2CCC(CCOC(c3ccc(F)cc3)c3ccc(F)cc3)CC2)cc1

InChI Key InChIKey=DRORTRSPMCSAOG-UHFFFAOYSA-N

Data  7 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50126820   

TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  1.20nMAssay Description:Affinity at rat dopamine transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  1.20nMAssay Description:Displacement of [125I]RTI55 from DAT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  6.90nMAssay Description:Inhibition of [3H]-dopamine uptake via rat dopamine receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransporter(Rattus norvegicus)
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  231nMAssay Description:Inhibition of [3H]-norepinephrine uptake at the rat norepinephrine transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  387nMAssay Description:Affinity at rat serotonin transporter using [125I]-RTI-55 displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  387nMAssay Description:Displacement of [125I]RTI55 from SERT in rat brain synaptosomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Niddk

Curated by ChEMBL
LigandPNGBDBM50126820(1-(4-nitrobenzyl)-4-(2-(bis(4-fluorophenyl)methoxy...)
Affinity DataKi:  1.56E+3nMAssay Description:Inhibition of [3H]-5-HT uptake at the rat serotonin transporter.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed