BDBM50127046 CHEMBL46913::N-((4S)-4-amino-5-{[4-(aminomethyl)phenyl]amino}pentyl)-N'-nitroguanidine

SMILES NCc1ccc(NC[C@@H](N)CCCNC(=N)N[N+]([O-])=O)cc1

InChI Key InChIKey=MCWPVZBUYYXHAR-NSHDSACASA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50127046   

TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  1.37E+3nMAssay Description:Inhibitory activity against Neuronal Nitric Oxide Synthase (nNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  1.37E+3nMAssay Description:Inhibitory activity against neuronal nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  3.35E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthaseChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  3.35E+5nMAssay Description:Inhibitory activity against Inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  4.09E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50127046(CHEMBL46913 | N-((4S)-4-amino-5-{[4-(aminomethyl)p...)
Affinity DataKi:  4.09E+5nMAssay Description:Inhibitory activity against endothelial nitric oxide synthase (eNOS)Checked by AuthorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed