BDBM50127136 CHEMBL1442185

SMILES Cc1ccccc1Cn1nnc2c1C(=O)c1ccccc1C2=O

InChI Key InChIKey=KEMMCAFUPKPXPJ-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50127136   

TargetTryptophan 2,3-dioxygenase(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50:  561nMAssay Description:Inhibition of recombinant human TDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50:  809nMAssay Description:Inhibition of recombinant human IDO expressed in Escherichia coli incubated for 1 hr measured by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human EGFR incubated for 2 hrs by Kinase-Glo luminescent kinase assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCatalase(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of catalase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of FLT3 (unknown origin) expressed in Sf9 insect cells for 4 hrs by Kinase-Glo assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 4(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 125I-SDF-1 from human CXCR4 expressed in HEK293 cells incubated for 1.5 hrs by Topcount analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50127136(CHEMBL1442185)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant mu-opioid receptor (unknown origin) expressed in CHO cells for 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed