BDBM50127307 4-{5-(3-Chloro-phenyl)-3-cyano-6-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-pyridin-2-yl}-piperazine-1-carboxylic acid tert-butyl ester::CHEMBL41936

SMILES Cn1cncc1C(OCc1nc(N2CCN(CC2)C(=O)OC(C)(C)C)c(cc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=CTLODRUWNFPOBN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127307   

LigandPNGBDBM50127307(4-{5-(3-Chloro-phenyl)-3-cyano-6-[(4-cyano-phenyl)...)
Affinity DataIC50:  0.990nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127307(4-{5-(3-Chloro-phenyl)-3-cyano-6-[(4-cyano-phenyl)...)
Affinity DataIC50:  650nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed