BDBM50127312 6-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-pyridine-2-carbonitrile::CHEMBL38438

SMILES Cn1cncc1C(OCc1ccc(nc1-c1cccc(Cl)c1)C#N)c1ccc(cc1)C#N

InChI Key InChIKey=DYDSFPPSNIDLGG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50127312   

LigandPNGBDBM50127312(6-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50:  0.820nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine FTaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGeranylgeranyl transferase type-1 subunit beta(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127312(6-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of transfer of [3H]-FPP to biotin K-ras peptide (KKSKTKCVIM) catalyzed by bovine GGTase-IMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed