BDBM50127354 (S)-3-[(3-Phenyl-ureido)-methyl]-3,4-dihydro-1H-isoquinoline-2-carbothioic acid [(R)-1-(2-methoxy-benzyl)-pyrrolidin-2-ylmethyl]-amide::CHEMBL40993

SMILES COc1ccccc1CN1CCC[C@@H]1CNC(=S)N1Cc2ccccc2C[C@H]1CNC(=O)Nc1ccccc1

InChI Key InChIKey=MQBFVOJTCPVYPE-IZLXSDGUSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50127354   

TargetMu-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50127354((S)-3-[(3-Phenyl-ureido)-methyl]-3,4-dihydro-1H-is...)
Affinity DataKi:  8.80nMAssay Description:Binding affinity for mu opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50127354((S)-3-[(3-Phenyl-ureido)-methyl]-3,4-dihydro-1H-is...)
Affinity DataKi:  109nMAssay Description:Binding affinity for kappa opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Astrazeneca R&D Montreal

Curated by ChEMBL
LigandPNGBDBM50127354((S)-3-[(3-Phenyl-ureido)-methyl]-3,4-dihydro-1H-is...)
Affinity DataKi:  509nMAssay Description:Binding affinity for delta opioid receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed