BDBM50127776 1-(4-Chloro-phenyl)-3-[2-(2,2,2-trifluoro-1-hydroxy-1-trifluoromethyl-ethyl)-naphthalen-1-yl]-urea::CHEMBL48174

SMILES OC(c1ccc2ccccc2c1NC(=O)Nc1ccc(Cl)cc1)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LSKGLHLOMINOAS-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50127776   

TargetATP-sensitive inward rectifier potassium channel 11(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50127776(1-(4-Chloro-phenyl)-3-[2-(2,2,2-trifluoro-1-hydrox...)
Affinity DataEC50:  276nMAssay Description:Potassium channel opening activity in vitro using LtK cells transfected with Kir6.2/SUR2B exon 17More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed