BDBM50128333 CHEMBL3629014
SMILES FC1(F)CCC(C1)n1nc(Nc2cc(ccn2)C#N)cc1C1CCN(CC1)C1COC1
InChI Key InChIKey=YRPUWZXFERSRBH-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50128333
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Wuxi Apptec
Curated by ChEMBL
Wuxi Apptec
Curated by ChEMBL
Affinity DataKi: 48nMAssay Description:Inhibition of N-terminally GST- tagged human DLK catalytic domain (1 to 520 amino acids) using N-terminally HIS-tagged MKK4 K131M as substrate incuba...More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase kinase kinase 12(Homo sapiens (Human))
Wuxi Apptec
Curated by ChEMBL
Wuxi Apptec
Curated by ChEMBL
Affinity DataIC50: 721nMAssay Description:Inhibition of Dox inducible human DLK transfected in HEK293 cells assessed as reduction in JNK phosphorylation incubated for 5.5 hrs measured by Hoec...More data for this Ligand-Target Pair