BDBM50128655 1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-piperidine-4-carboxylic acid hydroxyamide::1-(4-fluorobenzyl)-N-hydroxy-4-(4-methoxyphenylsulfonyl)piperidine-4-carboxamide::CHEMBL309416

SMILES COc1ccc(cc1)S(=O)(=O)C1(CCN(Cc2ccc(F)cc2)CC1)C(=O)NO

InChI Key InChIKey=HYZDHISHDZBYBQ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128655   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128655(1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50:  250nMAssay Description:In vitro inhibitory activity against tumor necrosis factor alpha converting enzyme (TACE).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128655(1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-9.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128655(1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50:  656nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50128655(1-(4-Fluoro-benzyl)-4-(4-methoxy-benzenesulfonyl)-...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed