BDBM50128922 CHEMBL3627950

SMILES CC(C(=O)NCc1ccc(cc1SC1CCCC1)C(F)(F)F)c1ccc(NS(C)(=O)=O)c(F)c1

InChI Key InChIKey=WIAXFFNFTIOWHI-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50128922   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50128922(CHEMBL3627950)
Affinity DataKi:  0.0300nMAssay Description:Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of NADA-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50128922(CHEMBL3627950)
Affinity DataKi:  0.300nMAssay Description:Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of capsaicin-induced activation by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50128922(CHEMBL3627950)
Affinity DataIC50:  37nMAssay Description:Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of low 45 degC heat -induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50128922(CHEMBL3627950)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human TRPV1 heterologously expressed in CHO cells assessed as inhibition of low pH-induced activationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed