BDBM50129170 7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-aza-chrysene::7-chloro-2,2,4-trimethyl-2,5-dihydro-1H-chromeno[3,4-f]quinoline::CHEMBL62714

SMILES CC1=CC(C)(C)Nc2ccc-3c(COc4c(Cl)cccc-34)c12

InChI Key InChIKey=CNWYJEBZDCMMPO-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50129170   

TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129170(7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataKi:  273nMAssay Description:Binding affinity at human progesterone receptor.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129170(7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataKi:  275nMAssay Description:Displacement of [3H]progesterone from Progesterone receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129170(7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataIC50:  782nMAssay Description:Effective concentration for human progesterone in T47D human breast cancer cellMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50129170(7-Chloro-2,2,4-trimethyl-2,5-dihydro-1H-6-oxa-1-az...)
Affinity DataEC50:  576nMAssay Description:Antagonistic activity at human progesterone receptor in CV-1 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed