BDBM50129486 (S)-N-[1-((S)-2-Amino-ethylcarbamoyl)-2-thiophen-2-yl-ethyl]-2-{3-[1-(2,6-dichloro-benzyl)-3-pyrrolidin-1-ylmethyl-1H-indol-6-yl]-ureido}-3-(3,4-difluoro-phenyl)-propionamide::CHEMBL71411

SMILES NCCNC(=O)[C@H](Cc1cccs1)NC(=O)[C@H](Cc1ccc(F)c(F)c1)NC(=O)Nc1ccc2c(CN3CCCC3)cn(Cc3c(Cl)cccc3Cl)c2c1

InChI Key InChIKey=AQHSZSZOLJQLMA-PXLJZGITSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129486   

TargetProteinase-activated receptor 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research & Development

Curated by ChEMBL
LigandPNGBDBM50129486((S)-N-[1-((S)-2-Amino-ethylcarbamoyl)-2-thiophen-2...)
Affinity DataIC50:  35nMAssay Description:Ability to inhibit the binding of [3H]-S-(p-F-Phe)-homoarginine-L-homoarginine-KY-NH2 to thrombin receptor on the membranes of CHRF-288-11 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed