BDBM50129534 5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H-pyrazole-3-carboxylic acid::CHEMBL307660

SMILES OC(=O)c1cc(-c2ccc(cc2)-c2ccc(Cl)cc2Cl)n(n1)-c1cccnc1

InChI Key InChIKey=XFMAKVCFFOHWFZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129534   

TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129534(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMethionine--tRNA ligase, cytoplasmic(Homo sapiens (Human))
Cubist Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50129534(5-(2',4'-Dichloro-biphenyl-4-yl)-1-pyridin-3-yl-1H...)
Affinity DataIC50:  4.70E+4nMAssay Description:Inhibitory activity against human methionyl-tRNA synthetase (hMetRS).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed