BDBM50130595 2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-dimethyl-phenyl]-propionic acid::CHEMBL105983::Dimethyl-isopropyl-T3 (DIMIT)

SMILES CC(C)c1cc(Oc2c(C)cc(C[C@H](N)C(O)=O)cc2C)ccc1O

InChI Key InChIKey=QHHWMOKQVCJRPS-KRWDZBQOSA-N

Data  4 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50130595   

TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  9.70nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  6.20nMAssay Description:Binding affinity of compound was determined against thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
University Of California San Francisco

LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  8.5nMAssay Description:Binding affinity of compound was determined against Thyroid hormone receptor alpha1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50130595(2-Amino-3-[4-(4-hydroxy-3-isopropyl-phenoxy)-3,5-d...)
Affinity DataKd:  9.80nMAssay Description:Human thyroid hormone receptor alpha and beta (hTR alpha1) and (hTR beta1) were produced using TNT coupled reticulocyte lysate system from Promega.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed