BDBM50131049 11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL312149

SMILES COc1ccc2c3CCn4c(nc5ccccc5c4=O)-c3[nH]c2c1

InChI Key InChIKey=POMASUJAYQAJQZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50131049   

TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131049(11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131049(11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...)
Affinity DataIC50:  1.98E+3nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University

Curated by ChEMBL
LigandPNGBDBM50131049(11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...)
Affinity DataIC50:  2.21E+4nMAssay Description:Inhibition of PDE5A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131049(11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...)
Affinity DataIC50:  110nMAssay Description:Inhibition of human CYP1B1 expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50131049(11-Methoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido...)
Affinity DataIC50:  110nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed