BDBM50131054 1,2-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one::CHEMBL85740

SMILES COc1ccc2c(nc3-c4[nH]c5ccccc5c4CCn3c2=O)c1OC

InChI Key InChIKey=QZAPJPSJZSHXDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131054   

TargetCytochrome P450 1A1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131054(1,2-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  970nMAssay Description:Inhibition of Cytochrome P450 1A1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1B1(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131054(1,2-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of Cytochrome P450 1B1 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
National Research Institute Of Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50131054(1,2-Dimethoxy-8,13-dihydro-7H-indolo[2',3':3,4]pyr...)
Affinity DataIC50:  29nMAssay Description:Inhibition of Cytochrome P450 1A2 enzyme in bacterial membrane expressing human P450sMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed