BDBM50131604 5-Benzo[1,3]dioxol-5-yl-4-chloro-1-(4-methanesulfonyl-phenyl)-1H-imidazole::CHEMBL326335

SMILES CS(=O)(=O)c1ccc(cc1)-n1cnc(Cl)c1-c1ccc2OCOc2c1

InChI Key InChIKey=DLTZICHLUOWHAV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131604   

TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131604(5-Benzo[1,3]dioxol-5-yl-4-chloro-1-(4-methanesulfo...)
Affinity DataIC50:  6nMAssay Description:In vitro percent inhibition of Prostaglandin G/H synthase 2 (COX-2) in human whole blood was determinedMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Homo sapiens (Human))
Domp&Egrove

Curated by ChEMBL
LigandPNGBDBM50131604(5-Benzo[1,3]dioxol-5-yl-4-chloro-1-(4-methanesulfo...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibitory activity against human Prostaglandin G/H synthase 1 (COX-1) in U-937 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed