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BDBM50131862 CHEMBL122938::methylphosphonic acid

SMILES: CP(O)(O)=O

InChI Key: InChIKey=YACKEPLHDIMKIO-UHFFFAOYSA-N

Data: 7 KI

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB:
Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50131862   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carbonic anhydrase 2


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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PubMed
98n/an/an/an/an/an/an/an/a



University of Montpellier

Curated by ChEMBL


Assay Description
Binding affinity towards human cytosolic carbonic anhydrase II


Bioorg Med Chem Lett 15: 1683-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.049
BindingDB Entry DOI: 10.7270/Q2NC60PJ
More data for this
Ligand-Target Pair
Carbonic Anhydrase VA


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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1.10E+5n/an/an/an/an/an/an/an/a



University of Montpellier

Curated by ChEMBL


Assay Description
Binding affinity towards recombinant human mitochondrial carbonic anhydrase V


Bioorg Med Chem Lett 15: 1683-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.049
BindingDB Entry DOI: 10.7270/Q2NC60PJ
More data for this
Ligand-Target Pair
Carbonic anhydrase 4


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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3.10E+5n/an/an/an/an/an/an/an/a



University of Montpellier

Curated by ChEMBL


Assay Description
Binding affinity towards human membrane associated carbonic anhydrase IV


Bioorg Med Chem Lett 15: 1683-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.049
BindingDB Entry DOI: 10.7270/Q2NC60PJ
More data for this
Ligand-Target Pair
Serine/threonine-protein phosphatase


(Enterobacteria phage lambda)
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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1.01E+6n/an/an/an/an/an/an/an/a



Utah State University

Curated by ChEMBL


Assay Description
Inhibitory activity against Serine/Threonine Protein Phosphatase (Lamda protein phosphatase)


J Med Chem 46: 3703-8 (2003)


Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN
More data for this
Ligand-Target Pair
Carbonic anhydrase 9


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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1.26E+6n/an/an/an/an/an/an/an/a



University of Montpellier

Curated by ChEMBL


Assay Description
Binding affinity owards recombinant human transmembrane carbonic anhydrase IX


Bioorg Med Chem Lett 15: 1683-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.01.049
BindingDB Entry DOI: 10.7270/Q2NC60PJ
More data for this
Ligand-Target Pair
Alkaline phosphatase placental-like


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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1.10E+7n/an/an/an/an/an/an/an/a



Utah State University

Curated by ChEMBL


Assay Description
Inhibition of Human Placental alkaline Phosphatase (PLAP)


J Med Chem 46: 3703-8 (2003)


Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN
More data for this
Ligand-Target Pair
Protein tyrosine phosphatase receptor type C-associated protein


(Homo sapiens (Human))
BDBM50131862
PNG
(CHEMBL122938 | methylphosphonic acid)
Show SMILES CP(O)(O)=O
Show InChI InChI=1S/CH5O3P/c1-5(2,3)4/h1H3,(H2,2,3,4)
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PubMed
3.00E+7n/an/an/an/an/an/an/an/a



Utah State University

Curated by ChEMBL


Assay Description
Inhibitory activity against Tyrosine phosphatase from Yersinia (Yop protein)


J Med Chem 46: 3703-8 (2003)


Article DOI: 10.1021/jm030106f
BindingDB Entry DOI: 10.7270/Q2MG7NXN
More data for this
Ligand-Target Pair