BDBM50132116 2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro-isoquinoline::CHEMBL126667

SMILES Fc1ccc(OCCCN2CCc3ccccc3C2)cc1

InChI Key InChIKey=UQNXMCNVFPEPNB-UHFFFAOYSA-N

Data  12 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50132116   

TargetD(4) dopamine receptor(RAT)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  83nMAssay Description:Displacement of [3H]N-methylspiperone from rat D4 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]LSD from human 5-HT7 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  166nMAssay Description:Displacement of [3H]N-methylspiperone from human D2 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  244nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  245nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  322nMAssay Description:Displacement of [3H]Ketanserin from human 5-HT2A receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  380nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  382nMAssay Description:Displacement of [3H]Pyrilamine from human H1 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 5A(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  400nMAssay Description:Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  561nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2B(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  562nMAssay Description:Displacement of [3H]LSD from human 5-HT2B receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Homo sapiens (Human))
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50132116(2-[3-(4-Fluoro-phenoxy)-propyl]-1,2,3,4-tetrahydro...)
Affinity DataKi:  769nMAssay Description:Displacement of [3H]N-methylspiperone from human D3 receptor expressed in cell membranes after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed