BDBM50132165 CHEMBL3349692::Ins (1,3,5)p3::Phosphoric acid mono-(2,4,6-trihydroxy-3,5-bis-phosphonooxy-cyclohexyl) ester

SMILES O[C@H]1[C@H](OP(O)(O)=O)[C@@H](O)[C@H](OP(O)(O)=O)[C@H](O)[C@@H]1OP(O)(O)=O

InChI Key InChIKey=RURWIJNHQMXJDV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132165   

TargetSphingomyelin phosphodiesterase(Homo sapiens)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50132165(CHEMBL3349692 | Ins (1,3,5)p3 | Phosphoric acid mo...)
Affinity DataIC50:  2.67E+4nMAssay Description:Inhibition of acid sphingomyelinase in human HuH7 cell lysate using NBD-sphingomyelin as substrate after 30 mins by TLC based fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInositol-trisphosphate 3-kinase A(Rattus norvegicus)
Pohang University Of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50132165(CHEMBL3349692 | Ins (1,3,5)p3 | Phosphoric acid mo...)
Affinity DataIC50:  9.00E+4nMAssay Description:Binding affinity of the compound against recombinant plasmid rat brain IP3K by overexpressing in E. coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed