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BDBM50132798 CHEMBL3634444

SMILES: Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12

InChI Key: InChIKey=OIRYAYABMIPBSY-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132798   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50132798
PNG
(CHEMBL3634444)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12
Show InChI InChI=1S/C24H15FN2O4/c1-13-11-12-31-21(13)22(28)26-18-9-10-19(15-6-3-2-5-14(15)18)27-23(29)16-7-4-8-17(25)20(16)24(27)30/h2-12H,1H3,(H,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 20n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of bovine trypsin


Bioorg Med Chem Lett 25: 5107-10 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.013
BindingDB Entry DOI: 10.7270/Q20C4XKQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4)


(Homo sapiens (Human))
BDBM50132798
PNG
(CHEMBL3634444)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12
Show InChI InChI=1S/C24H15FN2O4/c1-13-11-12-31-21(13)22(28)26-18-9-10-19(15-6-3-2-5-14(15)18)27-23(29)16-7-4-8-17(25)20(16)24(27)30/h2-12H,1H3,(H,26,28)
UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/a 809n/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR4 by calcium mobilization assay


Bioorg Med Chem Lett 25: 5107-10 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.013
BindingDB Entry DOI: 10.7270/Q20C4XKQ
More data for this
Ligand-Target Pair
Metabotropic glutamate receptor 1


(Homo sapiens (Human))
BDBM50132798
PNG
(CHEMBL3634444)
Show SMILES Cc1ccoc1C(=O)Nc1ccc(N2C(=O)c3cccc(F)c3C2=O)c2ccccc12
Show InChI InChI=1S/C24H15FN2O4/c1-13-11-12-31-21(13)22(28)26-18-9-10-19(15-6-3-2-5-14(15)18)27-23(29)16-7-4-8-17(25)20(16)24(27)30/h2-12H,1H3,(H,26,28)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 19n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Positive allosteric modulation of human mGluR1 by calcium mobilization assay


Bioorg Med Chem Lett 25: 5107-10 (2015)


Article DOI: 10.1016/j.bmcl.2015.10.013
BindingDB Entry DOI: 10.7270/Q20C4XKQ
More data for this
Ligand-Target Pair