BDBM50134549 CHEMBL3746891

SMILES NS(=O)(=O)c1ccc(cc1)N1N=C(CC1c1cccs1)c1cccs1

InChI Key InChIKey=JGZJHEIVVDMVFN-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50134549   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50134549(CHEMBL3746891)
Affinity DataKi:  24nMAssay Description:Binding affinity to human CA1 assessed as inhibition constant using p-Nitrophenylacetate as substrate by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Isf College Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50134549(CHEMBL3746891)
Affinity DataKi:  37nMAssay Description:Binding affinity to human CA2 assessed as inhibition constant using p-Nitrophenylacetate as substrate by SDS-PAGE analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50134549(CHEMBL3746891)
Affinity DataIC50:  1.64E+4nMAssay Description:Inhibition of ovine COX1 by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Beni-Suef University

Curated by ChEMBL
LigandPNGBDBM50134549(CHEMBL3746891)
Affinity DataIC50:  6.11E+3nMAssay Description:Inhibition of human recombinant COX2 by enzyme immuno assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed