BDBM50134638 CHEMBL3746315::US9637484, 30

SMILES Cc1ccc2nccc(SC3(CCC3)C(O)=O)c2c1

InChI Key InChIKey=NKWAZUCNSBQFEX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134638   

TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50134638(CHEMBL3746315 | US9637484, 30)
Affinity DataIC50:  343nMAssay Description:In vitro URAT1 assay can be used to identify compounds having potential activity for decreasing serum uric acid. In a suitable test, the vectors that...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetSolute carrier family 22 member 12(Homo sapiens (Human))
Shanghai Hengrui Pharmaceutical

US Patent
LigandPNGBDBM50134638(CHEMBL3746315 | US9637484, 30)
Affinity DataIC50:  343nMAssay Description:Inhibition of human URAT1 expressed in HEK293 cells assessed as [14C]uric acid uptake after 12 mins by scintillation counterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed