BDBM50134657 (4-Benzyl-piperidin-1-yl)-(5-hydroxy-1H-indol-2-yl)-methanone::(4-benzylpiperidin-1-yl)(5-hydroxy-1H-indol-2-yl)methanone::CHEMBL126228
SMILES Oc1ccc2[nH]c(cc2c1)C(=O)N1CCC(Cc2ccccc2)CC1
InChI Key InChIKey=PSSKCBVZPHCABL-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50134657
Affinity DataIC50: 42nMAssay Description:Inhibition of NMDA-evoked increased intracellular [Ca2+] in cells expressing NR1/NR2B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of N-methyl-D-aspartate glutamate receptor-evoked increase of intracellular Ca+ in cells expressing NMDA glutamate receptor 1/2BMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Displacement of [3H]Ro 25,6981 from NR2B NMDA receptor in rat forebrainMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 2B(Rattus norvegicus (Rat))
Gedeon Richter
Curated by ChEMBL
Gedeon Richter
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Antagonist activity at NR2B NMDA receptor in Wistar rat neocortical cells assessed as inhibition of NMDA-evoked elevation of intracellular calcium co...More data for this Ligand-Target Pair