BDBM50134925 CHEMBL2376666

SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(NS(N)(=O)=O)c1

InChI Key InChIKey=IWMDPOIAMPDYQT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50134925   

TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134925(CHEMBL2376666)
Affinity DataIC50:  14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134925(CHEMBL2376666)
Affinity DataIC50:  14nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134925(CHEMBL2376666)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134925(CHEMBL2376666)
Affinity DataIC50:  530nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed