BDBM50134925 CHEMBL2376666
SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(NS(N)(=O)=O)c1
InChI Key InChIKey=IWMDPOIAMPDYQT-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50134925
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG
Curated by ChEMBL
Bayer HealthCare AG
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG
Curated by ChEMBL
Bayer HealthCare AG
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair