BDBM50134939 CHEMBL3747359

SMILES NC(=O)c1c(Nc2ccc(I)cc2F)cc(F)cc1Oc1cccc(NS(N)(=O)=O)c1Cl

InChI Key InChIKey=SPLFQDSWYQVQLH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50134939   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134939(CHEMBL3747359)
Affinity DataIC50:  700nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer HealthCare AG

Curated by ChEMBL
LigandPNGBDBM50134939(CHEMBL3747359)
Affinity DataIC50:  18nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed