BDBM50135213 CHEMBL3747016
SMILES Cn1ccc(n1)-c1ccc(Cn2cc(C(=O)N[C@H]3CCOC[C@@H]3O)c3ncccc23)cc1
InChI Key InChIKey=FQGJDGJXEZTKDW-UNMCSNQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50135213
Affinity DataKi: 40nMAssay Description:In vitro inhibitory activity against [3H]- (+)-3-PPP binding to Sigma opioid receptor in guinea pig brain membrane homogenatesMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Positive allosteric modulation of human muscarinic M1 receptor expressed in CHO cells assessed as increase in ACh-induced intracellular calcium level...More data for this Ligand-Target Pair
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in calcium mobilization incubated for 10 m...More data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Positive allosteric modulation of human M1 receptor expressed in CHO cells assessed as acetylcholine-induced calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataEC50: 55nMAssay Description:Positive allosteric modulation of human muscarinic acetylcholine receptor M1 expressed in CHO cells assessed as increase in acetylcholine-induced cal...More data for this Ligand-Target Pair