BDBM50135258 (S)-1-[(2S,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)-2-methyl-piperidin-1-yl]-3-(2-methyl-benzofuran-4-yloxy)-propan-2-ol::CHEMBL129650

SMILES COc1cccc2sc(cc12)[C@@H]1CCN(C[C@H](O)COc2cccc3oc(C)cc23)[C@@H](C)C1

InChI Key InChIKey=NNWMNOCTZDIGBT-SXLOBPIMSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50135258   

Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135258((S)-1-[(2S,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  4.10nMAssay Description:Binding affinity towards 5-hydroxytryptamine 1A receptor in human using [3H]-8-OH-DPAT as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50135258((S)-1-[(2S,4R)-4-(4-Methoxy-benzo[b]thiophen-2-yl)...)
Affinity DataKi:  38nMAssay Description:Affinity at the 5-HT reuptake site labeled with [3H]-paroxetine using rat frontal cortex membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed