BDBM50135961 2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluoromethyl-2H-pyrazole-3-carboxylic acid (2'-methanesulfonyl-biphenyl-4-yl)-amide::CHEMBL151201

SMILES COc1ccc(c(CN)c1)-n1nc(cc1C(=O)Nc1ccc(cc1)-c1ccccc1S(C)(=O)=O)C(F)(F)F

InChI Key InChIKey=SBWNTOAALXMENS-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50135961   

TargetCoagulation factor X(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135961(2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluorometh...)
Affinity DataKi:  1.70nMAssay Description:Tested in vitro for inhibition of human Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135961(2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluorometh...)
Affinity DataKi: >1.60E+3nMAssay Description:Tested in vitro for inhibition of human trypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50135961(2-(2-Aminomethyl-4-methoxy-phenyl)-5-trifluorometh...)
Affinity DataKi:  9.10E+3nMAssay Description:In vitro for inhibition of human thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed