BDBM50136256 (1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydroxyamide 2-[(4-quinolin-6-ylethynyl-phenyl)-amide]::CHEMBL135177

SMILES ONC(=O)[C@H]1CCCC[C@@H]1C(=O)Nc1ccc(cc1)C#Cc1ccc2ncccc2c1

InChI Key InChIKey=JFZMYYGJKATRJG-VXKWHMMOSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50136256   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136256((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >2.13E+3nMAssay Description:Inhibition of matrix metalloproteinase-9(MMP-9)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136256((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >3.33E+3nMAssay Description:Inhibition of matrix metalloproteinase-2(MMP-2)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136256((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataKi: >4.95E+3nMAssay Description:Inhibition of matrix metalloproteinase-1(MMP-1)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Sus scrofa (pig))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50136256((1S,2S)-Cyclohexane-1,2-dicarboxylic acid 1-hydrox...)
Affinity DataIC50:  7.24E+3nMAssay Description:Inhibition of porcine TACEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed