BDBM50136518 (3R,4S)-4-Phenyl-pyrrolidine-3-carboxylic acid {(R)-3-[6-(4-chloro-phenylsulfanyl)-2-(4-methoxy-phenyl)-3-oxo-2,3-dihydro-pyridazin-4-yl]-1-methyl-propyl}-amide; hydrochloride::CHEMBL137452::CHEMBL541866
SMILES COc1ccc(cc1)-n1nc(Sc2ccc(Cl)cc2)cc(CC[C@@H](C)NC(=O)[C@H]2CNC[C@@H]2c2ccccc2)c1=O
InChI Key InChIKey=UCRUJXVEFBEWBN-UEFPSYNTSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50136518
Affinity DataIC50: 190nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
Affinity DataEC50: 400nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair
Affinity DataEC50: 405nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Effective concentration for cAMP accumulation relative to alpha-MSH at human MC4RMore data for this Ligand-Target Pair
Affinity DataEC50: 250nMAssay Description:Concentration required to inhibit binding of [125I]-NDP-alpha-MSH from membranes prepared from CHO cells expressing human melanocortin subtype-4-rece...More data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Effective concentration at human melanocortin 4 receptor in cAMP release assayMore data for this Ligand-Target Pair