BDBM50137124 4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid::4-chloro-2-(3-(naphthalen-2-yl)ureido)benzoic acid::CHEMBL346524

SMILES OC(=O)c1ccc(Cl)cc1NC(=O)Nc1ccc2ccccc2c1

InChI Key InChIKey=ODWUYZAAMNLBKT-UHFFFAOYSA-N

Data  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50137124   

TargetGlutamate receptor 4(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 4 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >3.00E+4nMAssay Description:Binding inhibition of compound against Ionotropic glutamate receptor ionotropic kainate 1 (GluR5) using [3H]-ATPA as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 2 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50:  6.20E+4nMAssay Description:In vitro inhibitory activity of the compound against Ionotropic glutamate receptor ionotropic kainate 2 (GluR-6) of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 3 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:In vitro inhibitory activity of the compound against Ionotropic glutamate receptor AMPA 1 of HEK293 cells in FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50:  6.90E+4nMAssay Description:In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 3(Rat)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR3 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 4(Rat)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR4 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 2(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at human homomeric GluR6 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50:  1.20E+3nMAssay Description:Antagonist activity at human homomeric GluR5 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >3.00E+4nMAssay Description:Displacement of [3HATPA from human recombinant GluR5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rat)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR2 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rat)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50: >1.00E+5nMAssay Description:Antagonist activity at rat homomeric recombinant GluR1 expressed in HEK293 cells assessed as inhibition of intracellular calcium concentration by FLI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 1(Human)
The Danish University of Pharmaceutical Sciences

Curated by ChEMBL
LigandPNGBDBM50137124(4-Chloro-2-(3-naphthalen-2-yl-ureido)-benzoic acid...)
Affinity DataIC50:  6.90E+4nMAssay Description:In vitro inhibitory activity against human ionotropic glutamate receptor ionotropic kainate 1 (GluR-5) expressed in HEK293 cells.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed