BDBM50137425 2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-(methylsulfonyl)pyridine::2-(3-Difluoromethyl-5-phenyl-pyrazol-1-yl)-5-methanesulfonyl-pyridine::CHEMBL174219

SMILES CS(=O)(=O)c1ccc(nc1)-n1nc(cc1-c1ccccc1)C(F)F

InChI Key InChIKey=LNEWNCVYPLKLFQ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50137425   

TargetProstaglandin G/H synthase 1(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  4.80E+4nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  4.80E+4nMAssay Description:Inhibitory activity against COX1 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  310nMAssay Description:Inhibition of COX2 by canine whole blood assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  310nMAssay Description:Inhibitory activity against COX2 in canine whole bloodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Canis familiaris)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50137425(2-(3-(difluoromethyl)-5-phenyl-1H-pyrazol-1-yl)-5-...)
Affinity DataIC50:  310nMAssay Description:In vitro inhibitory activity against cannine prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed