BDBM50138559 2-(7-Hydroxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-ylmethyl)-N-(4-phenyl-but-3-enyl)-benzamide::CHEMBL150560

SMILES Oc1ccc2CCN(Cc3ccccc3C(=O)NCC\C=C\c3ccccc3)CCc2c1

InChI Key InChIKey=YUYNUVNOOFKHBQ-UXBLZVDNSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50138559   

TargetSodium- and chloride-dependent glycine transporter 2(Homo sapiens (Human))
Pharmacopeia

Curated by ChEMBL
LigandPNGBDBM50138559(2-(7-Hydroxy-1,2,4,5-tetrahydro-benzo[d]azepin-3-y...)
Affinity DataIC50:  58nMAssay Description:Inhibitory activity against human glycine transporter type 2 (hGlyT2) expressed in Chinese hamster ovary (CHO) cell lineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed