BDBM50138739 4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazol-3-yl)-phenyl]-benzamide::4-tert-butyl-N-(4-(5-methoxy-2-oxo-1,3,4-oxadiazol-3(2H)-yl)phenyl)benzamide::CHEMBL339297

SMILES COc1nn(-c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(=O)o1

InChI Key InChIKey=QPUXQWSDBKIGCJ-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50138739   

TargetCholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against butyrylcholinesterase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPancreatic triacylglycerol lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Compound was tested to inhibit pancreatic lipase (PL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  23nMAssay Description:Inhibition of hormone sensitive lipase (HSL).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHormone-sensitive lipase(Rattus norvegicus (Rat))
University Of Jordan

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  0.410nMAssay Description:Inhibition of HSL in Wistar rat isolated fat cells by spectrophotometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibitory concentration against acetylcholinesteraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatic triacylglycerol lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  1.80E+3nMAssay Description:Compound was tested to inhibit hepatic lipase (HL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLipoprotein lipase(Homo sapiens (Human))
Novo Nordisk

Curated by ChEMBL
LigandPNGBDBM50138739(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Affinity DataIC50:  200nMAssay Description:Compound was tested to inhibit lipoprotein lipase (LPL)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed