BDBM50138777 CHEMBL414904::cyclo[Trp3]Dyn A-(1-11)NH2

SMILES CC[C@H](C)[C@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H]1CNC(=O)C[C@@H](NC(=O)[C@@H](N)Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2c[nH]c3ccccc23)C(=O)N[C@H](Cc2ccccc2)C(=O)N1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(N)=O

InChI Key InChIKey=PCMNBYSOCRMMCE-SUJAYCGQSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50138777   

TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50138777(CHEMBL414904 | cyclo[Trp3]Dyn A-(1-11)NH2)
Affinity DataKi:  1.33nMAssay Description:Binding affinity towards Opioid receptor kappa 1 expressed in CHO cells was determined by using [3H]-diprenorphine as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50138777(CHEMBL414904 | cyclo[Trp3]Dyn A-(1-11)NH2)
Affinity DataKi:  2.09nMAssay Description:Binding affinity towards Opioid receptor mu 1 expressed in CHO cells was determined by using[3H]DAMGO as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(MOUSE)
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50138777(CHEMBL414904 | cyclo[Trp3]Dyn A-(1-11)NH2)
Affinity DataKi:  7.07E+3nMAssay Description:Binding affinity towards opioid receptor delta 1 expressed in CHO cells was determined by using [3H]-DPDPE as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Rattus norvegicus (rat))
University Of Maryland

Curated by ChEMBL
LigandPNGBDBM50138777(CHEMBL414904 | cyclo[Trp3]Dyn A-(1-11)NH2)
Affinity DataEC50:  4.19nMAssay Description:Inhibition of forskolin-stimulated adenylyl cyclase activity by compound in CHO cells expressing Opioid receptor kappa 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed