BDBM50138800 CHEMBL3754094

SMILES CC(C)CN([C@H](C(C)C)C(=O)NO)S(=O)(=O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=WROMENMJKIPTLM-HXUWFJFHSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50138800   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  3nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  6.08E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 1 hr followed by the addition of 3.33 uM bradykinin like substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  2.26E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin pretreated with compound for 1 hr followed by the addition of 1.73 uM bradykinin like substrate by s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThermolysin(Bacillus thermoproteolyticus)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  2.43E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 15 mins followed by the addition of 75 uM Abz-Ala-Gly-leu-Ala-p-n...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50138800(CHEMBL3754094)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed