BDBM50140168 (E)-1-(2,4-dihydroxyphenyl)-3-(3-hydroxyphenyl)-2-propen-1-one (2)::(E)-3,2'',4''-Trihydroxychalcone::CHEMBL1083821
SMILES Oc1cccc(\C=C\C(=O)c2ccc(O)cc2O)c1
InChI Key InChIKey=WKMQGQZPDSFACZ-QPJJXVBHSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50140168
TargetBeta-secretase 1(Homo sapiens (Human))
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
Shanghai Institute Of Material Medica, Chinese Academy Of Sciences
Affinity DataIC50: 8.03E+3nMpH: 4.5 T: 2°CAssay Description:The assay based on fluorescenceresonance energy transfer was carried out with BACE1 enzyme at pH 4.5 with a substrate, H-Lys(DABSYL)-SEVNLDAEFR-Gin-(...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University
Curated by ChEMBL
Guangxi Medical University
Curated by ChEMBL
Affinity DataIC50: 1.08E+5nMAssay Description:Inhibition of bovine milk xanthine oxidase pre-incubated for 30 mins followed by xanthine addition and measured every 30 secs for 5 mins by spectroph...More data for this Ligand-Target Pair
TargetXanthine dehydrogenase/oxidase(Bos taurus (Bovine))
Guangxi Medical University
Curated by ChEMBL
Guangxi Medical University
Curated by ChEMBL
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of bovine xanthine oxidase assessed as conversion of xanthine to uric acid by spectroscopic analysisMore data for this Ligand-Target Pair