BDBM50140672 (2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-thia-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid::Beta-lactam compound, 2::CHEMBL25613

SMILES CC1(C)S[C@@H]2[C@H](CO)C(=O)N2[C@H]1C(O)=O

InChI Key InChIKey=DJIMYYWAZIOWRD-JCGDXUMPSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50140672   

TargetOxa40(Acinetobacter baumannii)
York University

LigandPNGBDBM50140672((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-th...)
Affinity DataKi:  3.00E+4nMAssay Description:Beta-lactam compounds were assessed as competitive inhibitors using nitrocefin as a reporter substrate.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase TEM(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140672((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-th...)
Affinity DataIC50:  7.52E+5nMAssay Description:Beta-Lactamase inhibitory activity against representative class A (TEM-1) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase type 2(Bacillus cereus)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140672((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-th...)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of class B (BCII) metallo-beta-lactamase representative enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetallo-beta-lactamase L1 type 3(Stenotrophomonas maltophilia)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140672((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-th...)
Affinity DataIC50: >2.00E+5nMAssay Description:Beta-Lactamase Inhibition of metallo-beta-lactamase representative class B (L1) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-lactamase(Escherichia coli)
Southern Methodist University

Curated by ChEMBL
LigandPNGBDBM50140672((2S,5R,6R)-6-Hydroxymethyl-3,3-dimethyl-7-oxo-4-th...)
Affinity DataIC50:  4.09E+5nMAssay Description:Beta-Lactamase inhibitory activity against representativeclass C (P99) serine enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed