BDBM50140871 4-{4-[2-(3,4-Difluoro-phenyl)-ethyl]-piperazin-1-yl}-5H-pyrimido[5,4-b]indol-9-ylamine::CHEMBL25972
SMILES Nc1cccc2[nH]c3c(ncnc3c12)N1CCN(CCc2ccc(F)c(F)c2)CC1
InChI Key InChIKey=AUDMYQPWPLNCSU-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50140871
Affinity DataIC50: 1.90E+3nMAssay Description:In vitro inhibitory activity against MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell line in accumulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.79E+4nMAssay Description:In vitro inhibitory activity against P-glycoprotein expressed in murine mammary carcinoma (EMT6/AR1.0 cell line) in accumulation assayMore data for this Ligand-Target Pair
Affinity DataIC50: 708nMAssay Description:Inhibitory activity against MRP1 (Multidrug resistance associated protein 1) expressed in COR.L23/R cell line in single-dose potentiation assayMore data for this Ligand-Target Pair