BDBM50141010 6-(5-Chloro-2-methyl-benzyl)-5-methyl-pyrido[2,3-d]pyrimidine-2,4-diamine::CHEMBL34775

SMILES Cc1ccc(Cl)cc1Cc1cnc2nc(N)nc(N)c2c1C

InChI Key InChIKey=WCXBBZIDKOPNRB-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50141010   

TargetDihydrofolate reductase(Homo sapiens (Human))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141010(6-(5-Chloro-2-methyl-benzyl)-5-methyl-pyrido[2,3-d...)
Affinity DataIC50:  0.190nMAssay Description:Inhibitory concentration against dihydrofolate reductase of Mycobacterium aviumMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Rattus norvegicus (rat))
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM50141010(6-(5-Chloro-2-methyl-benzyl)-5-methyl-pyrido[2,3-d...)
Affinity DataIC50:  2.80nMAssay Description:Inhibitory concentration against dihdrofolate reductace enzyme of humansMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed